BCM7 found in A1 milk is known to have opioid or narcotic side effects and is identified to be the culprit of lactose intolerance in 1 out 4 Americans. A1 is considered a genetic mutation that results in the production of the compound BCM7 assumed to be causing the development of unwanted health conditions and illnesses among consumers. There are also studies that showed that drinking A1 or A2 milk has no effect on overall behavior (34). You need to make the right choices to seek the best quality. This mutation in the amino acid chain link of A1 milk is supposed to cause adverse effects in humans, whilst making A2 milk the healthier option. This makes no sense! Even plain old lettuce has around 30-40mg/100g. Is A1 Milk the Major Cause of Lactose Intolerance? Milk produced by A1 cows supposedly produces opiate-like effects resulting in the development of mild to serious medical conditions (2). The a2 Corporation petitioned the Food Standards Australia New Zealand (FSANZ) regulatory authority to have these health warnings added to all containers of its A1 milk rivals. In one study, high levels of BCM-7 in the bloodstream were found among infants suffering from sleep apnea or temporary breathing patterns during sleep. Warnings – A1 vs. A2 Milk! Many of us not aware of a2 Milk Health Benefits. The difference between A1 and A2 beta-casein is as tiny as can be—a single amino acid in the long chain that makes this protein. A2 milk is produced by A2 Milk Company, and contains no A1 beta-casein. Due to some observation from these studies, there are some nutritionists who have started recommending parents of children with autism to start supplementing their diets with A2 milk. For medical advice, diagnosis or treatment, consult a medical practitioner. A1 and A2 milk feature the same lactose concentrations. Autism is a developmental disorder characterized by disabilities including problems with social interaction, communication, and repetitive behaviors. The difference between A1 and A2 is in the amino acid chain number 67. There is not enough human trials that can prove the hypothesis that A1 and A2 milk have significant impact on the incidence and severity of autism symptoms (35, 36). The only difference between A1 and A2 is a difference in the 67th amino acid in the chain. Wouldn’t the best way to avoid the ills of milk be to just not drink it (regardless of the root cause of those ills or the superior A2 to A1 ratio of certain cow breeds)? Type 1 Diabetes Mellitus is an autoimmune disease that typically develops in children. When you take an A1/A2 animal and breed to an A2/A2 bull, you have a 50% chance at an A2A2. BCM7 (Beta-casomorphin-7), an opioid peptide in A1 beta-casein is produced as a result of the breaking off of histidine in the number 67 amino acid chain during digestion (9, 10). I shall be amending this, probably changing the picture even. According to the California Research Foundation (http://cdrf.org/2017/02/09/a2-milk-facts/) Jersey contain the A2 beta casein. Another study reveals that drinking cow’s milk over time may potentially exacerbate the symptoms among children with autism. BCM-7 penetration into a newborn’s central nervous system may potentially inhibit normal respiratory system functioning as evidenced by abnormal respiratory breathing, hypoxia, and excessive levels of carbon dioxide resulting in sudden death (30). The makers of A2 milk contend that lactose is not the real suspect for the development of lactose intolerance, but a mutation caused by A1 beta-casein, a compound found in store-brought milk and dairy products. Over time, there were infants that showed the ability to metabolize BCM-7 at a fast rate, whilst there are those who showcased inability to process and excrete BCM-7 and other peptides altogether. Studies reveal that BCM-7 is absent in the blood of healthy adults, whilst presence of BCM-7 in infants is a possibility (15, 16, 17). Some researchers hypothesized that BCM-7 from A1 beta-casein may be the culprit in some cases of SIDs. There are also reports that show no difference in the effects of A1 and A2 milk in children. It was theorized that BCM-7 plays a crucial role in the development of autism in children. even raw milk sometimes does. In one study involving 41 men and women, results revealed that drinking A1 milk may result in softer stools than A2 milk consumption in some test subjects. The A1 gene mutation began hundreds of years ago from Holstein cow breed that was then passed onto other breeds (8). I appreciated the reporting, found it interesting, but am amused at the bias in the comment section and questionnaire response. This makes A1 susceptible to splitting apart during digestion. When compared alongside A2 beta-casein, A1 showcased similar effects on blood pressure levels, blood vessel function, blood fats concentration, and inflammatory markers (27). That one amino acid change means when the A1 protein is broken down, it can create the peptide BCM-7. Despite numerous studies that point to the increased risk of coronary heart disease in animals, there are no solid evidence that can confirm the negative effects of A1 beta-casein in humans. A1 and A2 beta casein proteins are made up of 209 amino acid chains. To date, there are only two human studies that have tested the effects of A1 beta-casein as a predisposing factor of heart disease. The results derived from the study tell us that there are no serious adverse effects on heart disease risk factors. Despite extensive and ongoing research, the extent of BCM-7 absorption into the bloodstream still remains unknown. A2 Milk Vs. A1 Milk. a2 Milk is 100% natural fresh desi cow’s milk which you may find easier to digest than regular cow milk.Here’s why: Cow milk contains different types of proteins – including the ones called a1 and a2. We are a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for us to earn fees by linking to Amazon.com and affiliated sites. The original claim about boring old A1 milk was that it may cause diseases ranging from autism and schizophrenia to type 1 diabetes and heart disease. The shortage of proof that switching to A2 milk intake can make a huge impact on health and wellness has made it impossible to boycott the sales, use, and continuous production of milk and dairy products from A1 cow breeds. Based on epidemiological evidence, the consumption of A1 milk is a contributing factor in the increased risk of development diabetes type 1 among children (12, 15, 18, 19). Gir Cow A2 Milk comes from cows with hump on back, they naturally produce only A2 protein beneficial and not A1 – and that makes all the difference. It's an especially rich source of calcium that is very "bio-available", which means you can absorb lots of it easily. Melatonin and Alcohol Interactions: What Happens When You Mix Them? Thus many regard it as the better type of casein protein. As research continues, the debate about the potential benefits and risks of A1 and A2 milk remains underway. In a study conducted by Russian researchers, high amounts of BCM-7 were found in the urine of infants with autism that were fed with milk formula. Major improvements have been observed among children who regularly consume A2 milk sourced from Guernsey cows due to its high A2 beta casein at 95%. In the year 2000, the a2 Corporation was formed to commercialise the A2 protein in a brand of milk. Prednisone and Alcohol Interactions: Can You Drink on Prednisone? The inflammatory nature of BCM-7 can affect lactase activity/production and possibly worsen existing hypolactasia and consequently lactose malabsorption symptoms in susceptible people. This genetic testing makes A2 milk more expensive. The most common cause of death in infants less than one year of age is identified to be Sudden Infant Death Syndrome or SIDS. Got Milk? One study included 15 male and female test subjects with known high risk of heart disease. (The research is scant on both claims; more on that in a second.) Based on the results derived from the other study, there are no significant differences in the effects of A1 and A2 beta-casein on blood cholesterol levels (26). The crossover design of the study meant that participants consumed both A1 and A2 beta-casein at different periods of time (26, 27). KEY POINT: A1 beta-casein is assumed to stimulate the development of type-1 diabetes in children. BCM-7 has been shown to have some minor effects on the gut movements and inflammation of animals, but this has not been conclusively shown in humans. Your picture diagram of the 5 cows is inaccurate. Although there have been numerous studies trying to link A1 milk to autism, there are still no solid proof that can verify this hypothesis (31, 32, 33). A1 vs. A2 Milk: The Bottom Line. Camel Milk? According to a 1992 observational study by Elliot RB, there was low incidence of diabetes mellitus type 1 among infants who were breastfed in the Polynesian Islands as opposed to Polynesian infants in Auckland that were supplied with commercial milk formulations containing A1 beta-casein (20). There is only one amino acid difference between the A1 amino acid strand compared to the A2 amino acid strand. What does the research say about A1 vs A2? My understanding is cows do not only produce one protein or the other, rather a different proportion of each eg 80℅ A2 20% A1, therefore the milk is going through yet another stage of processing to meet their marketing claims. If you found this article helpful, follow us on facebook and/or share the article with buttons below so other people can benefit from it too: You can republish this article on your blog/website by complying with the following republishing guidelines. Image: Udderly complicated: A1 vs A2 milk (Flickr: Zeyus Media CC BY 2.0) It was once claimed that A1 milk could cause diseases ranging from autism and schizophrenia to … Both A1 and A2 are proteins in the casein family, which makes up about one-third of all the proteins in human milk, but about 80 per cent of the proteins in cow's milk. A1 has histidine at position 67, while A2 has proline. A2 milk is milk from mother dairy cows that have been bred to not produce the A1 beta-casein protein—a form of the casein protein in milk. . There is an ongoing debate about the nutritional value of both A1 and A2 milk. We need accurate information so people can be properly informed. http://cdrf.org/2017/02/09/a2-milk-facts/. It’s a myth you need milk for calcium (and protein for that matter). Cow 1 which has a lable of “a1” is a Jersey cow, yet you have described below that Jersey cows are “a2”. In the 5 years testing and breeding A1/A2 cows to A2A2 bulls, one out of every 10 heifers have been A2A2. The experiment on rabbits clearly showed that the accumulation of fats may potentially clog and block blood vessels that may result in heart disease. Due to limited studies, there are no concrete evidence that can link SIDS to the death of infants that exclusively consumed A1 milk formulations. KEY POINT: The difference between A1 and A2 is in the amino acid chain number 67. That is 50% each year, but never seems to pencil out to being one in two animals ;). In 2005, independent researcher Stewart Truswell carried out a comprehensive investigation of the A1 and A2 proteins. So correct me if I’m wrong, histadine is an essential amino acid (we must consume it) but we are better to eliminate it from milk (A1 milk) and replace it with A2 that contains proline a non-essential amino acid instead? Although there are reports that show positive benefits of drinking A2 milk, there is not enough data to support the hypothesis that A1 beta-casein can trigger or worsen the symptoms of lactose intolerance. These risks are not generally found with A2 milk consumption. Making the switch from common A1 milk to A2 milk is supposed to be beneficial for child afflicted with autism. It is claimed A1 milk consumption produces harmful health effects, yet these harmful effects are not present when drinking A2 milk. 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